How does testosterone improve mood?
Hormone replacement therapy (HRT), specifically testosterone replacement therapy (TRT), strongly elevates men’s mood. It sparks enthusiasm and increases a man’s interest in activities, other people, and life in general. It’s been said, testosterone is one of the top three natural antidepressant substances.
Testosterone is similar in many ways to thyroid hormones, and thyroid hormones are the equivalent of strong anti-depressants. Both testosterone and thyroid hormones produce antidepressant effects by significantly increasing production of many important other hormones. This revitalizes almost the entire endocrine (hormone) system, which explains why their antidepressant effect may outclass that of pharmaceutical antidepressants, whose effect on the endocrine system commonly inhibits hormone production, reducing endocrine effects. For example, Fluoxetine (Prozac) reduces the suppression of oxytocin, a hormone associated with warm-hearted feelings, affection for others, social interaction, and even orgasms, which explains why people taking this type of drug may smile less and present less emotion.
Results for depression are not always consistent, but TRT has been repeatedly shown to improve states of depression, like those experienced by men around age-40 or those who do not respond to antidepressants as desired.
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